Dosing & Administration

Oral and IV Monotherapy Dosing
With BAXDELA® (delafloxacin)

Oral or IV q12h dosing options for 5 to 14 days

  • 450-mg tablet q12h

OR

  • 300-mg IV infusion administered over 1 hour q12h
    • Provided as a lyophilized powder in vials

OR

  • Transition from IV to oral BAXDELA at the discretion of the physician

No Oral Dosage Adjustment Required Due To:

image group referencing age(adult), weight, sex
image group referencing mild to moderate renal disease, hepatic disease

Oral or IV BAXDELA is not recommended in patients with End Stage Renal Disease (ESRD) (eGFR <15 mL/min/1.73 m2), including patients on hemodialysis, due to insufficient information for dosing recommendations.

Fixed-Dosage Adjustment in IV Formulation for Patients with Severe Renal Impairment (eGFR 15-29 mL/min/1.73 m2)

  • 200 mg IV q12h

OR

  • 200 mg IV q12h, then switch to a 450-mg BAXDELA tablet orally q12h at the discretion of the physician
BAXDELA® is indicated in adults for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by designated susceptible bacteria.